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Systematic determination of the mosaic structure of bacterial genomes: species backbone versus strain-specific loops
Authors:Email author" target="_blank">H?ChiapelloEmail author  I?Bourgait  F?Sourivong  G?Heuclin  A?Gendrault-Jacquemard  M-A?Petit  M?El Karoui
Institution:1.Mathématique,Informatique & Génome,Jouy-en-Josas cedex,France;2.Unité de Recherches Laitières et Génétique Appliquée,Jouy-en-Josas cedex,France
Abstract:

Background  

Public databases now contain multitude of complete bacterial genomes, including several genomes of the same species. The available data offers new opportunities to address questions about bacterial genome evolution, a task that requires reliable fine comparison data of closely related genomes. Recent analyses have shown, using pairwise whole genome alignments, that it is possible to segment bacterial genomes into a common conserved backbone and strain-specific sequences called loops.
Keywords:
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