In vitro activity of levamisole on the infective larvae, microfilariae and adult worms of Breinlia Sergenti |
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Authors: | P N Natarajan V Zaman T S Yeoh |
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Institution: | 1. School of Pharmacy University of Singapore, Singapore 3 Singapore;2. Faculty of Medicine, University of Singapore, Singapore 3 Singapore |
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Abstract: | In vitro activity of levamisole on the infective larvae, microfilariae and adult worms of Breinlia sergenti. International Journal for Parasitology4: 207–210. Levamisole shows in vitro activity against the infective larvae, microfilariae and adult worms of Breinlia sergenti. The polygraph studies using the adult worms indicate that levamisole causes an increase in the muscle tone; this action being dose related. The adult worms are more sensitive to the drug than the infective larvae and microfilariae. In vitro, levamisole is more potent compared with diethylcarbamazine against all the three stages of B. sergenti. |
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Keywords: | Levamisole adults microfilarial infective larvae |
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