Synthesis,physico-chemical studies of manganese(II), cobalt(II), nickel(II), copper(II) and zinc(II) complexes with some p-substituted acetophenone benzoylhydrazones and their antimicrobial activity |
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| Authors: | Vinod P. Singh Shweta Singh Anshu Katiyar |
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| Affiliation: | Chemistry Department, Banaras Hindu University, Varanasi-221005, India |
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| Abstract: | Complexes of the type [M(pabh)(H2O)Cl], [M(pcbh)(H2O)Cl] and [M(Hpabh)(H2O)2 (SO4)] where, M = Mn(II), Co(II), Ni(II), Cu(II) and Zn(II); Hpabh = p-amino acetophenone benzoyl hydrazone and Hpcbh = p-chloro acetophenone benzoyl hydrazone have been synthesized and characterized with the help of elemental analyses, electrical conductance, magnetic susceptibility measurements, electronic, ESR and IR spectra, thermal (TGA & DTA) and X-ray diffraction studies. Co(II), Ni(II) and Cu(II) chloride complexes are square planar, whereas their sulfate complexes have spin-free octahedral geometry. ESR spectra of Cu(II) complexes with Hpabh are axial and suggest ![/></span> as the ground state. The ligand is bidentate bonding through >C = N ? and deprotonated enolate group in all the chloro complexes, whereas, >C = N and >C = O groups in all the sulfato complexes. Thermal studies (TGA & DTA) on [Cu(Hpabh)(H<sub>2</sub>O)<sub>2</sub>(SO<sub>4</sub>)] indicate a multistep decomposition pattern, which are both exothermic and endothermic in nature. X-ray powder diffraction parameters for [Co(pabh)(H<sub>2</sub>O)Cl] and [Ni(Hpabh)(H<sub>2</sub>O)<sub>2</sub>(SO<sub>4</sub>)] correspond to tetragonal and orthorhombic crystal lattices, respectively. The ligands as well as their complexes show a significant antifungal and antibacterial activity. The metal complexes are more active than the ligand.</td>
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| Keywords: | Metal complexes synthesis physico-chemical studies p-substituted acetophenone benzoylhydrazone antimicrobial |
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