Enantioselective inclusion complexation of 2,3,4,6-tetra-O-acetyl-D-glycopyranose as a chiral host with (+)-(r)-phenylethylamine: x-ray characterization of the complex

X-ray analysis of the crystalline product obtained by reaction of 2,3,4,6-Tetra-O-acetyl-D-glycopyranose with phenylethylamine revealed the formation of a real one-to-one inclusion complex. This complexaion is highly stereoselective, because only the (+)-R-enantiomeric form of the amine is included. Analogies to the mode of complexation of cellulose triaceate with chiral molecules in ?inclusion chromatography”? are discussed.