Sponge (2',5')oligoadenylate synthetase activity in the whole sponge organism and in a primary cell culture |
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Authors: | Kelve Merike Kuusksalu Anne Lopp Annika Reintamm Tõnu |
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Institution: | Laboratory of Molecular Genetics, National Institute of Chemical Physics and Biophysics, Akadeemia tee 23, 12618, Tallinn, Estonia. merike@kbfi.ee |
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Abstract: | A high (2',5')oligoadenylate (2-5A) synthetase activity was found in the marine sponge Geodia cydonium. Here we demonstrate that the 2-5A synthetase activity is present also in other sponge species although the level of the 2-5A synthetase activity varies in several magnitudes in different sponges. The 2-5A synthesizing activity was maintained in the primary culture produced from a sponge. |
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