13/14 translocation in a man with reproductive failure |
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Authors: | Miroslava D Mi?i? Jovanka G Nikoli? Sava R Mi?i? |
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Institution: | (1) Faculty of Stomatology and Medicine, Institute of Biology and Human Genetics, 11000 Belgrade, Yugoslavia;(2) Faculty of Medicine, Urology Clinic, Generala danova 51, 11000 Belgrade, Yugoslavia |
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Abstract: | Summary An inherited (maternal origin) 13/14 translocation with the nucleolus organizer regions eliminated and one centromere was found in an oligospermic man whose wife had had two spontaneous abortions. Meiotic studies revealed all stages of spermatogenesis with a trivalent configuration in diakinesis. Possible reasons for his subfertility and his mother's normal fertility are discussed. |
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