Dopamine increases cyclic AMP concentration in the rat spleen lymphocytes in vitro |
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| Authors: | H Stepień J Kunert-Radek E Karasek M Pawlikowski |
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| Affiliation: | Department of Experimental Endocrinology and Hormone Chemistry, Institute of Endocrinology, Medical Academy of ?ód?, 91-425 ?ód?, Dr. Sterling 3, Poland |
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| Abstract: | The effect of dopamine on the cyclic AMP concentration in the rat spleen lymphocytes has been investigated . It has been shown that dopamine in concentration above 10?6M induces a significant increase of cyclic AMP level. The maximal stimulatory effect was observed after 10 minutes of the lymphocytes incubation with dopamine. These data suggest that the dopamine receptor in lymphocyte belongs to D-1 category. |
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