GLIDERS - A web-based search engine for genome-wide linkage disequilibrium between HapMap SNPs |
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| Authors: | Robert Lawrence Aaron G Day-Williams Richard Mott John Broxholme Lon R Cardon Eleftheria Zeggini |
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| Affiliation: | (1) Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK;(2) Wellcome Trust Sanger Institute, Hinxton, UK;(3) Fred Hutchinson Cancer Research Center, Seattle, Washington, USA;(4) GlaxoSmithKline, King of Prussia, Pennsylvania, USA |
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| Abstract: | ![]()
Background A number of tools for the examination of linkage disequilibrium (LD) patterns between nearby alleles exist, but none are available for quickly and easily investigating LD at longer ranges (>500 kb). We have developed a web-based query tool (GLIDERS: Genome-wide LInkage DisEquilibrium Repository and Search engine) that enables the retrieval of pairwise associations with r2 ≥ 0.3 across the human genome for any SNP genotyped within HapMap phase 2 and 3, regardless of distance between the markers. |
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