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Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting
Authors:Mark R. Sullivan  Katherine R. Mattaini  Emily A. Dennstedt  Anna A. Nguyen  Sharanya Sivanand  Montana F. Reilly  Katrina Meeth  Alexander Muir  Alicia M. Darnell  Marcus W. Bosenberg  Caroline A. Lewis  Matthew G. Vander Heiden
Affiliation:1. Koch Institute for Integrative Cancer Research, Cambridge, MA, USA;2. Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;3. Department of Pathology, Yale University School of Medicine, New Haven, CT, USA;4. Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA;5. Whitehead Institute for Biomedical Research, Cambridge, MA 02139, USA;6. Dana-Farber Cancer Institute, Boston, MA 02215, USA;7. Broad Institute, Cambridge, MA 02139, USA
Abstract:
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  • Keywords:Corresponding author  serine  PHGDH  melanoma  breast cancer
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