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The Ischemic Stroke Genetics Study (ISGS) Protocol
Authors:James?F?Meschia  author-information"  >  author-information__contact u-icon-before"  >  mailto:Meschia.James@mayo.edu"   title="  Meschia.James@mayo.edu"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author,Thomas?G?Brott,Robert?D?Brown  Suffix"  >Jr,Richard?JP?Crook,Michael?Frankel,John?Hardy,José?G?Merino,Stephen?S?Rich,Scott?Silliman,Bradford?Burke?Worrall
Affiliation:(1) Department of Neurology, Mayo Clinic, Jacksonville, Florida, U.S.A;(2) Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, U.S.A;(3) Emory University School of Medicine, Atlanta, Georgia, U.S.A;(4) National Institute on Aging, Bethesda, Maryland, U.S.A;(5) University of Florida/Shands Hospital, Jacksonville, Florida, U.S.A;(6) Department of Public Health Sciences and Neurology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, U.S.A;(7) University of Virginia Health System, Charlottesville, Virginia, U.S.A
Abstract:

Background  

The molecular basis for the genetic risk of ischemic stroke is likely to be multigenic and influenced by environmental factors. Several small case-control studies have suggested associations between ischemic stroke and polymorphisms of genes that code for coagulation cascade proteins and platelet receptors. Our aim is to investigate potential associations between hemostatic gene polymorphisms and ischemic stroke, with particular emphasis on detailed characterization of the phenotype.
Keywords:
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