Developmental analysis of lethal effects of homozygosity for the C25H deletion in the mouse |
| |
Authors: | Susan E Lewis |
| |
Institution: | Department of Genetics, Albert Einstein College of Medicine, New York, New York 10461 USA |
| |
Abstract: | This report describes the phenotype of the c25H lethal homozygote. Our studies have shown that embryos homozygous for c25H fail to implant and to induce a decidual reaction. Embryos arrested at the three- to six-cell stage were considered to be c25H homozygotes because of their homogeneous stage of arrest and because they were present in the appropriate proportion in preimplantation litters from matings. Mitosis appeared to be disturbed in the arrested embryos. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |