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Approaching mathematical model of the immune network based DNA Strand Displacement system
Authors:Rizki Mardian  Kosuke SekiyamaToshio Fukuda
Affiliation:Department of Micro-Nano Systems Engineering, Nagoya University, Furo-cho, Chikusa, Nagoya, Japan
Abstract:
One biggest obstacle in molecular programming is that there is still no direct method to compile any existed mathematical model into biochemical reaction in order to solve a computational problem. In this paper, the implementation of DNA Strand Displacement system based on nature-inspired computation is observed. By using the Immune Network Theory and Chemical Reaction Network, the compilation of DNA-based operation is defined and the formulation of its mathematical model is derived. Furthermore, the implementation on this system is compared with the conventional implementation by using silicon-based programming. From the obtained results, we can see a positive correlation between both. One possible application from this DNA-based model is for a decision making scheme of intelligent computer or molecular robot.
Keywords:DNA Strand Displacement   Chemical Reaction Network   Immune Network Theory   Molecular programming   Mathematical model
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