Radiation-induced dominant lethal mutations in oocytes of Musca domestica |
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Authors: | Hamilton João Targa Clovis A. Peres |
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Affiliation: | Departamento de Biologia, Instituto de Biociências, Universidade de São Paulo, Caixa Postal 11 461, 05421 São Paulo, Brazil;Departamento de Estatística, Instituto de Matemática e Estatística, Universidade de São Paulo, Caixa Postal 20570, 01451 São Paulo, Brazil |
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Abstract: | Dominant lethal mutations induced by γ-radiation were measured in stage-7 and stage-14 oocytes of Musca domestica. At both stages the data are consistent with the multi-hit theory on radiation induction of dominant lethals. This conclusion is supported by fractionation experiments which indicate that both] S7 and S14 oocytes are capable of repairing, in defferent periods of time, a similar amount of dominant lethal damage. |
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