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Molecular motors: single-molecule recordings made easy
Authors:Diez Stefan  Schief William R  Howard Jonathon
Affiliation:Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstr. 108, 01307 Dresden, Germany.
Abstract:
A fusion protein of kinesin and gelsolin binds a short actin filament which can be visualized using a standard fluorescence microscope. This technique has provided new insight into the mechanism of kinesin action, and in principle it can be extended to allow single-molecule assays of any protein.
Keywords:
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