单切口和双切口联合手术对闭角型青光眼合并白内障患者视力、IOP及CCT的影响

目的:探讨单切口和双切口联合手术对闭角型青光眼合并白内障患者视力、眼压(IOP)及中央前房深度(CCT)的影响。方法:选择2013年6月至2016年6月我院收治的90例闭角型青光眼合并白内障患者,随机分为观察组和对照组,每组各45例。对照组采用单切口手术治疗,观察组采用双切口手术治疗。观察并比较两组患者治疗前后角膜内皮细胞密度、面积、最佳矫正视力、裸眼视力、IOP以及术后并发症的发生率。结果:与术前比较,两组患者术后角膜内皮细胞密度均升高,且观察组高于对照组,差异具有统计学意义(P0.05);与术前比较,两组患者术后角膜内皮细胞面积均减小,且观察组小于对照组,差异具有统计学意义(P0.05);与术前比较,两组患者术后最佳矫正视力、裸眼视力均升高,且观察组高于对照组,差异具有统计学意义(P0.05);与术前比较,两组患者术后IOP均降低,且观察组低于对照组,差异具有统计学意义(P0.05);与术前比较,两组患者术后CCT均升高,且观察组高于对照组,差异具有统计学意义(P0.05);观察组术后并发症总发生率低于对照组(P0.05)。结论:双切口手术治疗闭角型青光眼合并白内障的效果显著,能够有效改善患者视力、IOP及CCT水平,且安全性高,值得临床推广。

Effects of Single and Double Incisions Operation on Visual Acuity, IOP and CCT in Patients with Angle Closure Glaucoma and Cataract

ABSTRACT Objective: To study the effects of single and double incisions operation on visual acuity, IOP and CCT in patients with angle closure glaucoma complicated with cataract. Methods: 90 patients with angle-closure glaucoma and cataract from June 2013 to June 2016 who were treated in our hospital were researched and randomly divided into the observation group and the control group, with 45 cases in each group. The patients in the control group were treated with single incision operation, while the patients in the observation group were treated with double incision operation. Then the corneal endothelial cell density and area, the best corrected visual acuity and naked eye visual acuity, the IOP, the CCT and the incidence of postoperative complications in the two groups were observed and compared. Results: Compared with before operation, the corneal endothelial cell density in the two groups increased after operation, and the observation group was higher than that of the control group, and the differences were statistically significant (P<0.05); Compared with before operation, the corneal endothelial cell area in the two groups decreased after operation, and the observation group was lower than that of the control group, and the differences were statistically significant (P<0.05); Compared with before operation, the best corrected visual acuity and naked eye visual acuity in the two groups increased after operation, and the observation group were higher than those of the control group, and the differences were statistically significant (P<0.05); Compared with before operation, the IOP in the two groups decreased after operation, and the observation group was lower than that of the control group, and the differences were statistically significant (P<0.05); Compared with before operation, the CCT in the two groups increased after operation, and the observation group was higher than that of the control group, and the differences were statistically significant (P<0.05); The incidence of postoperative complications in the observation group was lower than that of the control group (P<0.05). Conclusion: Double incision surgery has better clinical effects on the treatment of the angle closure glaucoma combined with cataract, which can effectively improve the visual acuity, IOP, and CCT with high security, and it is worthy of clinical application.