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Synthesis of thioanalogs of platelet activating factor (PAF) |
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| Authors: | K Iu Gordeev G A Serebrennikova R P Evstigneeva |
| Abstract: | Synthesis of thioalkyl, thioacetyl and phosphothionyl PAF analogues was carried out starting with corresponding monoalkyl glycerol ethers. The synthetic route was based on preparation of racemic phosphatidylcholines and subsequent hydrolysis with phospholipase A2 to afford isomers having natural configuration. |
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