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Antifungal activity of the termite alkaloid norharmane against the mycelial growth of Metarhizium anisopliae and Aspergillus nomius
Authors:Chouvenc Thomas  Su Nan-Yao  Elliott Monica I
Institution:a Department of Entomology and Nematology, University of Florida, FL, USA
b Department of Plant Pathology, University of Florida, FL, USA
c Ft. Lauderdale Research and Education Center, University of Florida, Institute of Food and Agricultural Sciences, 3205 College Avenue, Ft. Lauderdale, FL 33314, USA
Abstract:Antifungal activity of norharmane, a β-carboline alkaloid found in termites (Isoptera, Rhinotermitidae) was tested against two entomopathogenic fungi, Metarhizium anisopliae and Aspergillus nomius. It was determined that, at physiological concentration (10 μg ml−1), norharmane had no significant effect on A. nomius mycelial growth rate but reduced M. anisopliae growth rate by 11.9%. Contrary to previous findings, we suggest that norharmane has a limited role in disease resistance against fungal pathogens in individual subterranean termites, and we discuss the potential role of this chemical at a colony level.
Keywords:Termite  Metarhizium  Aspergillus  Norharmane  Disease resistance  Antifungal activity
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