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Sex-Specific Effects of Cis-Regulatory Variants in Drosophila melanogaster |
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| Authors: | Joseph D Coolon William Webb Patricia J Wittkopp |
| Institution: | *Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan 48109;†Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109 |
| Abstract: | Sexual dimorphism at the level of gene expression is common and well documented, but much less is known about how different cis-regulatory alleles interact with the different trans-regulatory environments present in males and females. Here we show that sex-specific effects of cis-regulatory variants are common in Drosophila. |
| Keywords: | gene regulation trans-regulation epistasis imprinting allele-specific expression |