Unnoticed spread of class 1 integrons in gram-positive clinical strains isolated in Guangzhou, China |
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Authors: | Shi Lei Zheng Meiping Xiao Zenghuang Asakura Masahiro Su Jianyu Li Lin Yamasaki Shinji |
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Institution: | College of Food and Biological Engineering, South China University of Technology. |
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Abstract: | A total of 46 gram-positive bacteria isolated from clinical specimens collected in China were subjected to PCR analysis with the intI1-specific primers, and the intI1-positive strains were further analyzed for their resistance gene cassette. All isolates possessed the class 1 integron in their genomes and the array of gene cassettes was dhfrXII-orfF-aadA2, which is very similar to other organisms except in one isolate carrying an additional copy of the class 1 integron containing the aadA2 gene cassette. Altogether, the results indicate that the class 1 integron is widespread in gram-positive clinical strains isolated in Guangzhou, China. |
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Keywords: | integrons gene cassettes gram‐positive bacteria |
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