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| 铅对雄性生殖毒性的研究进展 | |
| 引用本文： | 汪美贞,贾秀英. 铅对雄性生殖毒性的研究进展[J]. 动物学杂志, 2006, 41(1): 123-127 |
| 作者姓名： | 汪美贞 贾秀英 |
| 作者单位： | 杭州师范学院生命科学学院,杭州,310036;杭州师范学院生命科学学院,杭州,310036 |
| 基金项目： | 浙江省自然科学基金资助项目(No.302056) |
| 摘 要： | 从铅对睾丸与附睾形态、精子生成和发育以及生殖内分泌功能等三方面的影响综述了铅对雄性生殖毒性的研究进展;并从铅对睾丸的脂质过氧化损伤,对睾丸标志酶活性的影响,对染色体、DNA及基因的影响以及对CaM、Ca2 -ATP酶活性的影响等方面探讨了铅对雄性生殖毒性作用机理。同时,提出了铅对雄性生殖毒性的研究中存在的若干问题和发展方向。 |
| 关 键 词： | 铅 雄性生殖毒性 |
| 文章编号： | 0250-3263（2006）01-123-05 |
| 收稿时间： | 2005-05-20 |
| 修稿时间： | 2005-05-202005-11-17 |
Reproductive Toxicity of Lead in Males |
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| WANG Mei-Zhen,JIA Xiu-Ying. Reproductive Toxicity of Lead in Males[J]. Chinese Journal of Zoology, 2006, 41(1): 123-127 | |
| Authors: | WANG Mei-Zhen JIA Xiu-Ying |
| Affiliation: | School of Life Sciences, Hangzhou Normal College, Hangzhou 310036,China |
| Abstract: | The paper summarizes the recent advances in reproductive toxicity of lead in males,including the effects of lead on morphology of testis and epididymis,spermatogenesis,and reproductive endocrine.Meanwhile,the mechanisms of male reproductive toxicity of lead are discussed.Lead may exert its toxic effect through influencing lipid peroxidation,marker enzyme activity,chromosomes,DNA and genes,as well as CaM and Ca~(2 )-ATPase activity.Finally,some problems and research trend in the research of lead's male reproductive toxicity are raised. |
| Keywords: | Lead Male reproductive toxicity |
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