| 播散性马尔尼菲篮状菌病1例 |
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| 引用本文： | 吴荣群,徐文英,李丽丽,陈杏春,韦海明,谢治.播散性马尔尼菲篮状菌病1例[J].中国真菌学杂志,2021(2):128-130,140. |
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| 作者姓名： | 吴荣群 徐文英 李丽丽 陈杏春 韦海明 谢治 |
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| 作者单位： | 广西壮族自治区人民医院皮肤性病科;广西壮族自治区人民医院检验科;广西壮族自治区人民医院病理科 |
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| 摘 要： | 患者,男,32岁,反复淋巴结肿大、发热伴皮疹2年,广谱抗生素、抗结核治疗无效,肺部CT提示两肺内多发结节,血γ干扰素抗体阳性,皮肤活检组织、淋巴结组织、肺穿刺活检组织均培养出马尔尼菲篮状菌,予两性霉素B脂质体联合伏立康唑治疗效果佳。
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| 关 键 词： | 马尔尼菲篮状菌病 非艾滋病患者 γ干扰素抗体 |
A case of disseminated Talaromyces marneffei |
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| WU Rongqun,XU Wenying,LI Lili,CHEN Xingchun,WEI Haiming,XIE Zhi.A case of disseminated Talaromyces marneffei[J].Chinese JOurnal of Mycology,2021(2):128-130,140. |
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| Authors: | WU Rongqun XU Wenying LI Lili CHEN Xingchun WEI Haiming XIE Zhi |
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| Institution: | (Guangxi Zhuang Autonomous Region People′s Hospital, Department of Dermatology,Nanning 530000, China;Guangxi Zhuang Autonomous Region People′s Hospital, Department of Laboratory Medicine,Nanning 530000, China;Guangxi Zhuang Autonomous Region People′s Hospital,Department of Pathology,Nanning 530000, China) |
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| Abstract: | A 32-year-old man was admitted because of recurrent episodes of lymphadenectasis,fever and skin rashes for two years.Broad-spectrum antibiotics and anti-tuberculosis therapy were ineffective.Lung CT showed multiple nodules in both lungs and the serum was positive for anti-IFN-γ.Disseminated Talaromyces marneffei was diagnosed by skin biopsy,lymph node biopsy,lung biopsy.Amphotericin B liposome combined with voriconazole had a good therapeutic effect. |
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| Keywords: | Talaromyces marneffei non-HIV patient anti-IFN-γautoantibody |
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