A natural surfactant from pig lungs |
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| Authors: | Flávia S. Kubrusly Solange de Lima Netto Dmitri Iourtov Isaias Raw Pedro Soares de Araujo |
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| Affiliation: | (1) Centro de Biotecnologia, Instituto Butantan, Av. Vital Brazil, 1500, CEP 05503-900 São Paulo-SP, Brazil;(2) Departamento de Bioquímica, Instituto de Química, USP, São Paulo-SP, Brazil |
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| Abstract: | ![]()
An exogenous natural lung surfactant obtained from minced pig lungs can be produced by a technology using a low cost, DEAE-cellulose adsorbent. This surfactant is composed mainly with phospholipids and the two hydrophobic polypeptides, SP-B and SP-C, both of which are necessary for optimal function of surfactants used for treatment of respiratory distress syndrome. |
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| Keywords: | lung surfactant purification technology respiratory distress syndrome |
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