| 虫草菌素药理学研究进展 |
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| 引用本文： | 康冀川,康超,文庭池,钱一鑫,雷帮星.虫草菌素药理学研究进展[J].菌物学报,2011,30(2):191-197. |
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| 作者姓名： | 康冀川 康超 文庭池 钱一鑫 雷帮星 |
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| 作者单位： | 1. 贵州大学西南药用生物资源教育部工程研究中心,贵阳,550025
2. 贵州大学西南药用生物资源教育部工程研究中心,贵阳,550025;贵州大学生命科学学院,贵阳,550025 |
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| 基金项目： | 贵州省中药现代化项目（2007）5012；贵州省教育厅自然科学研究重点项目[No. 黔教科（2009）0129号]；贵州省科学技术基金项目（No. 黔科合J字[2008]2089） |
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| 摘 要： | 虫草菌素是一种脱氧核苷类似物,对多种疾病都有潜在的治疗作用。综述了国内外虫草菌素药理学的研究概况,主要概括了虫草菌素在调节免疫、抗肿瘤、抗真菌、抗病毒、抗白血病、降血糖、降血脂等方面的研究进展。提出了虫草菌素在临床应用时存在的问题,并对如何开展虫草菌素药理学研究及其应用进行了展望。
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| 关 键 词： | 虫草菌素 药理活性 作用机理 临床应用 |
Pharmacological research progress of cordycepin |
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| Authors: | KANG Ji-Chuan KANG Chao WEN Ting-Chi QIAN Yi-Xin and LEI Bang-Xing |
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| Institution: | The Engineering and Research Center for Southwest Bio-Pharmaceutical Resources of National Education Ministry of China, Guizhou University, Guiyang 550025, China;The Engineering and Research Center for Southwest Bio-Pharmaceutical Resources of National Education Ministry of China, Guizhou University, Guiyang 550025, China
College of Life Sciences, Guizhou University, Guiyang 550025, China;The Engineering and Research Center for Southwest Bio-Pharmaceutical Resources of National Education Ministry of China, Guizhou University, Guiyang 550025, China;The Engineering and Research Center for Southwest Bio-Pharmaceutical Resources of National Education Ministry of China, Guizhou University, Guiyang 550025, China;The Engineering and Research Center for Southwest Bio-Pharmaceutical Resources of National Education Ministry of China, Guizhou University, Guiyang 550025, China |
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| Abstract: | Cordycepin(3'-deoxyadenosine),a nucleoside analog,is reported to possess many pharmacological activities.It was regarded as the agent responsible for immunological regulation,anti-tumor,antifungal action,anti-virus,anti-leukemia,antidiabetics and hypolipidaemic activities.This is a review dealing with the problems in the clinical application,the prospects of future development and the pharmacological activities of cordycepin. |
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| Keywords: | cordycepin pharmacological activities mechanism of action clinical application |
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