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A comparison of the ouabain-sensitive (Na+ + K+)-ATPase of normal and dystrophic skeletal muscle
Authors:Garth M. Bray
Affiliation:Division of Neurology, Department of Medicine, The Montreal General Hospital and McGill University, Montreal, Quebec Canada
Abstract:
An NaI-extraction procedure was modified to prepare muscle fiber segments with Mg2+-dependent, ouabain-sensitive (Na+ + K+)-ATPase activity. This enzyme was assayed in preparations of skeletal muscle from normal and dystrophic mice. The ouabain-sensitive (Na+ + K+)-ATPase activity of dystrophic muscle preparations was found to be significantly lower than that of control preparations.
Keywords:EGTA
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