Histone3 variants in plants

Regulation of chromatin activity by covalent histone modifications has been long recognized. Histones that constitute the nucleosome are encoded by large families of genes and display a strong degree of conservation. However, histone variants exist and it is becoming clear that they play important roles in genome regulation. While most studies of the role of histone3 (H3) variants in transcriptional control comes from animal models, emerging data in plants suggest functional conservation, although plant-specific roles are likely. We review these data and speculate on the biological significance of H3 variants in plants.