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Plus-strand origin for human immunodeficiency virus type 1: implications for integration.
Authors:K A Pullen and J J Champoux
Affiliation:Department of Microbiology, School of Medicine, University of Washington, Seattle 98195.
Abstract:The start site for human immunodeficiency virus type 1 plus strands within the polypurine tract was mapped by an in vitro analysis to the sequence 5'-ACTG....From this result, it can be inferred that integration of human immunodeficiency virus type 1 must be accompanied by the loss of two base pairs from the polypurine tract-primed long terminal repeat end.
Keywords:
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