Scatchard plot: Common misinterpretation of binding experiments |
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Authors: | Jens G. Nørby Paul Ottolenghi Jørgen Jensen |
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Affiliation: | 1. Institute of Biophysics, University of Aarhus, DK-8000 Aarhus C, Denmark;2. Institute of Physiology, University of Aarhus, DK-8000 Aarhus C, Denmark |
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Abstract: | The widespread misinterpretation in the literature of ligand-protein binding experiments which show upward curvature in Scatchard plots is emphasized. The most commonly encountered errors are discussed and references to the correct methods of resolution of upward-curved Scatchard plots are given. |
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Keywords: | To whom all correspondence should be addressed. |
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