Expression of superoxide dismutases in the bovine oviduct during the estrous cycle |
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| Authors: | Roy M Gauvreau D Bilodeau J-F |
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| Institution: | Unité de Recherche en Ontogénie et Reproduction, Centre de Recherche du Centre Hospitalier de l'Université Laval, Québec, Canada G1V 4G2; Centre de Recherche en Biologie de la Reproduction (CRBR), Université Laval, Québec, Canada GIV 4G2. |
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| Abstract: | The superoxide dismutases (SODs) are first-line enzymatic antioxidants that dismute superoxide anion (O(2)(-)) to produce hydrogen peroxide (H(2)O(2)). The primary objective was to characterize, by western blot analysis, the expression of two SODs, the cytosolic (Cu,ZnSOD or SOD1) and the mitochondrial (MnSOD or SOD2) forms in three sections of the oviduct, i.e. isthmus (I), ishtmic-ampullary junction (IA), and ampulla (A), during the estrous cycle. The Cu,ZnSOD and MnSOD proteins were mostly expressed in the ampulla (I
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