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Caspase cleavage releases a nuclear protein fragment that stimulates phospholipid scrambling at the plasma membrane
Authors:Masahiro Maruoka  Panpan Zhang  Hiromi Mori  Eiichi Imanishi  Daniel M. Packwood  Hiroshi Harada  Hidetaka Kosako  Jun Suzuki
Affiliation:1. Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, Yoshida-Honmachi, Sakyoku, Kyoto 606-8501, Japan;2. Graduate School of Biostudies, Kyoto University, Konoe-cho, Yoshida, Sakyoku, Kyoto 606-8501, Japan;3. AMED-FORCE, Japanese Agency for Medical Research and Development, 1-7-1 Otemachi, Chiyodaku, Tokyo 100-0004, Japan;4. Center for Integrated Biosystems, Institute for Biomedical Sciences, Academia Sinica, Taipei, Taiwan;5. Fujii Memorial Institute of Medical Sciences, Tokushima University, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan
Abstract:
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  • Keywords:Phospholipid scrambling  Phosphatidylserine  Efferocytosis  Xkr4  Caspase  Nuclear fragment  CRISPR-Cas9 sgRNA library screening  XRCC4  DNA repair  cDNA library screening
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