Multiple organism algorithm for finding ultraconserved elements |
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| Authors: | Scott Christley Neil F Lobo Greg Madey |
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| Affiliation: | (1) Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, IN 46556, USA;(2) Interdisciplinary Center for the Study of Biocomplexity, University of Notre Dame, Notre Dame, USA;(3) Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, 46556, USA |
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| Abstract: | Background Ultraconserved elements are nucleotide or protein sequences with 100% identity (no mismatches, insertions, or deletions) in the same organism or between two or more organisms. Studies indicate that these conserved regions are associated with micro RNAs, mRNA processing, development and transcription regulation. The identification and characterization of these elements among genomes is necessary for the further understanding of their functionality. |
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