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Synthesis,insecticidal, and fungicidal screening of some new quinoline derivatives |
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| Authors: | M R E Aly M M Ibrahim A M Okael Y A M H Gherbawy |
| Institution: | 1. Chemistry Department, Faculty of Science, Taif University, Alhawyah-Taif, 888, Kingdom of Saudi Arabia 2. Chemistry Department, Faculty of Applied Science, Port Said University, Port Said, 42522, Egypt 3. Chemistry Department, Faculty of Science, Kafr El Sheikh University, Kafr El-Sheikh, 33516, Egypt 4. Plant Protection Research Institute, ARC, Dokki, Cairo, Egypt 5. Biology Department, Faculty of Science, Taif University, Alhawyah-Taif, KSA 6. Botany Department, Faculty of Science, South Valley University, Qena, Egypt |
| Abstract: | This paper describes the synthesis of a series of quinolines graphted with hydrazones, pyrazoles, pyridazine, phthalazine, triazepinone, semicarbazide, and thiomorpholide moieties and four metal complexes. These derivatives were screened against Fusarium oxysporum and the red palm weevil (RPW) Rhynchophorus ferrugineus Oliver (coleopteran: Curculionidae) as palm pathogens. Only chlorinated quinolines were active against these organisms with hydrazones being good fungicides, while those modified with pyrazoles and pyrazines showed moderate insecticidal activity. A unique trihydroxylated hydrazone was active against both organisms, while another hydrazone, the most potent fungicide in this series, exhibited insecticidal activity only upon complexation with Zn2+ ions. |
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