Synthesis and terminal functionalization of a polymerizable phosphatidylethanolamine |
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Authors: | Sun X L Liu H Orban J M Sun L Chaikof E L |
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Affiliation: | Laboratory for Biomolecular Materials Research, Department of Surgery and Bioengineering, Emory University School of Medicine, Atlanta, Georgia 30322, USA. |
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Abstract: | ![]() We report the design and synthesis of bifunctional phospholipid conjugates, which contain a polymerizable acrylate group and a terminal linker, such as biotin or N-(epsilon-maleimidocaproyl (EMC), to facilitate bioconjugation reactions. The lipid conjugate can be used to generate a multifunctional substrate-supported phospholipid film that is further stabilized via in-situ photocopolymerization. |
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