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Preclinical Evaluation of a Novel TALEN Targeting CCR5 Confirms Efficacy and Safety in Conferring Resistance to HIV-1 Infection |
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| Authors: | Marianna Romito Alexandre Juillerat Yik Lim Kok Markus Hildenbeutel Manuel Rhiel Geoffroy Andrieux Johannes Geiger Carsten Rudolph Claudio Mussolino Aymeric Duclert Karin J Metzner Philippe Duchateau Toni Cathomen Tatjana I Cornu |
| Institution: | 1. Institute for Transfusion Medicine and Gene Therapy, Center for Chronic Immunodeficiency, Medical Center—University of Freiburg, Freiburg, 79106 Germany
Faculty of Medicine, University of Freiburg, Freiburg, 79110 Germany;2. Cellectis, Inc., New York, NY, 10016 USA;3. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, 8091 Switzerland Institute of Medical Virology, University of Zurich, Zurich, 8057 Switzerland;4. Faculty of Medicine, University of Freiburg, Freiburg, 79110 Germany Institute of Medical Bioinformatics and Systems Medicine, Medical Center – University of Freiburg, Freiburg, 79110 Germany German Cancer Consortium (DKTK), Freiburg, Germany and German Cancer Research Center (DKFZ), Heidelberg, 69120 Germany;5. ethris GmbH, Planegg, 81249 Germany;6. Cellectis S.A., Paris, 75013 France;7. Institute for Transfusion Medicine and Gene Therapy, Center for Chronic Immunodeficiency, Medical Center—University of Freiburg, Freiburg, 79106 Germany |
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