Volatile Nitrogenous Compounds from Bacteria: Source of Novel Bioactive Compounds |
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| Authors: | Camilla A S Valença Ana A T Barbosa Eliana B Souto Elina B Caramão Sona Jain |
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| Institution: | 1. Programa de Pós-Graduação em Biotecnologia Industrial, Universidade Tiradentes, Aracaju, Sergipe, Brazil;2. Department of Morphology, Universidade Federal de Sergipe, São Cristóvão, Sergipe, Brazil;3. CEB – Center of Biological Engineering, Universidade do Minho, Campus de Gualtar, 4710-057 Braga, Portugal;4. Programa de Pós-Graduação em Biotecnologia Industrial, Universidade Tiradentes, Aracaju, Sergipe, Brazil
Instituto Nacional de Ciência e Tecnologia - Energia e Ambiente, Universidade Federal da Bahia, Salvador, Bahia, Brazil |
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| Abstract: | Bacteria can produce nitrogenous compounds via both primary and secondary metabolic processes. Many bacterial volatile nitrogenous compounds produced during the secondary metabolism have been identified and reported for their antioxidant, antibacterial, antifungal, algicidal and antitumor activities. The production of these nitrogenous compounds depends on several factors, including the composition of culture media, growth conditions, and even the organic solvent used for their extraction, thus requiring their identification in specific conditions. In this review, we describe the volatile nitrogenous compounds produced by bacteria especially focusing on their antimicrobial activity. We concentrate on azo-compounds mainly pyrazines and pyrrolo-pyridines reported for their activity against several microorganisms. Whenever significant, extraction and identification methods of these compounds are also mentioned and discussed. To the best of our knowledge, this is first review describing volatile nitrogenous compounds from bacteria focusing on their biological activity. |
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| Keywords: | nitrogenous compounds antioxidant activity antibacterial activity antifungal activity antitumor activity |
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