A Novel Simian Immunodeficiency Virus (SIVdrl) pol Sequence from the Drill Monkey, Mandrillus leucophaeus |
| |
| Authors: | J. P. Clewley J. C. M. Lewis D. W. G. Brown E. L. Gadsby |
| |
| Affiliation: | Virus Reference Division, Central Public Health Laboratory, London,1. and International Zoo Veterinary Group, Keighley,2. United Kingdom, and Drill Rehabilitation and Breeding Center, Calabar, Nigeria3. |
| |
| Abstract: | The drill monkey has been shown by serology and PCR to harbor a unique simian immunodeficiency virus (SIVdrl). A pol sequence, amplified from uncultured peripheral blood cells, is most closely related to the equivalent SIV sequences from the red-capped mangabey (SIVrcm), the sabaeus African green monkey (SIVagmSAB), and the chimpanzee (SIVcpz) and to the human immunodeficiency virus type 1 (HIV-1) sequence of humans. It is as yet unclear whether SIVdrl has a mosaic genome like SIVrcm and SIVagmSAB, is a member of the SIVcpz/HIV-1 lineage, or represents a novel primate lentivirus lineage. |
| |
| Keywords: | |
|
|
