Neurohumoral mechanisms of the rat heart adaptation to overload |
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Authors: | V. N. Fedorov M. M. Fateev E. V. Salnikov A. V. Sidorov |
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Affiliation: | 1.Yaroslavl State Medical Academy,Yaroslavl,Russia |
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Abstract: | The present study confirms involvement of the sympathicoadrenal system in adaptation of heart to overload. Besides, at formation of chronic heart failure (CHF) there have been revealed a rise of the histamine and serotonin levels in blood plasma and myocardium as well as glucocorticoid hyperactivation. |
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