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Efficacy-Driven Dose Finding with Toxicity Control in Phase I Oncology Studies |
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| Authors: | Liu Qingyang Geng Junxian Fleischer Frank Deng Qiqi |
| Institution: | 1.University of Connecticut, Storrs, CT, USA ;2.Boehringer-Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA ;3.Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany ; |
| Abstract: | Statistics in Biosciences - Traditionally, dose-finding process for oncology compound is carried out in phase I dose escalation study and is driven by safety in order to find maximum tolerated dose... |
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| 本文献已被 SpringerLink 等数据库收录！ | |