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| 脑内膜雌激素受体信号转导与窖蛋白 | |
| 引用本文： | 韩丹女,徐祎慧,马依妮,崔玉影,张冬艳,邹伟. 脑内膜雌激素受体信号转导与窖蛋白[J]. 生物技术通讯, 2011, 22(3): 442-444. DOI: 10.3969/j.issn.1009-0002.2011.03.031 |
| 作者姓名： | 韩丹女 徐祎慧 马依妮 崔玉影 张冬艳 邹伟 |
| 作者单位： | 1. 辽宁师范大学,生命科学学院 2. 辽宁师范大学,生命科学学院;辽宁省生物技术和分子药物研发重点实验室,辽宁,大连,116029 |
| 摘 要： | 雌激素受体在脑内分布十分广泛,对脑功能具有重要作用。雌激素可以通过膜雌激素受体启动的信号转导通路(非基因组效应)作用于中枢神经系统的很多部位,而窖蛋白(caveolin)可以通过不同方式参与膜雌激素受体介导的脑功能调节。简要综述了脑内膜雌激素受体介导的信号转导通路与窖蛋白相关的研究进展。 |
| 关 键 词： | 膜雌激素受体 窖蛋白 信号转导 脑 |
The Membrane Initiated Estrogen Signal Transduction and Caveolin in Brain |
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| HAN Dan-nv,XU Yi-Hui,MA Yi-Ni,CUI Yu-Ying,ZHANG Dong-Yan,ZOU Wei. The Membrane Initiated Estrogen Signal Transduction and Caveolin in Brain[J]. Letters in Biotechnology, 2011, 22(3): 442-444. DOI: 10.3969/j.issn.1009-0002.2011.03.031 | |
| Authors: | HAN Dan-nv XU Yi-Hui MA Yi-Ni CUI Yu-Ying ZHANG Dong-Yan ZOU Wei |
| Affiliation: | 1,2 1.College of Life Science,Liaoning Normal University;2.Liaoning Key Laboratories of Biotechnology and Molecular Drug Research and Development;Dalian 116029,China |
| Abstract: | Estrogen receptors（ER） are widely expressed in brain which play an important role in the brain function.Recent study showed that estrogen can make some effects on multiple parts of central nervous system by membrane-initiated estrogen signaling pathway,the non-genomic pathway.And caveolin can take part in the brain function mediated by ER in different patterns.In this paper,the correlation of ER and caveolin will be summarized and discussed. |
| Keywords: | membrane estrogen receptor caveolin signal transduction brain |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |