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High-resolution analyses of associations between medications,microbiome, and mortality in cancer patients
Institution:1. Gerstner Sloan Kettering Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;2. Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;3. Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;4. Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA;5. Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;6. Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;7. Program for Computational and Systems Biology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;8. Division of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA;9. Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;10. Duchossois Family Institute, University of Chicago, Chicago, IL 60637, USA;1. Institut Pasteur, Université Paris Cité, CNRS UMR6047, Archaeal Virology Unit, Paris 75015, France;2. Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22903, USA;3. Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35233, USA;4. Fujian Provincial Key Laboratory of Soil Environmental Health and Regulation, College of Resources and Environment, Fujian Agriculture and Forestry University, Fuzhou 350002, Fujian, China;5. O’Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35233, USA;1. Picower Institute for Learning & Memory, Department of Brain & Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA;2. Computational and Systems Biology Program, Massachusetts Institute of Technology, Cambridge, MA, USA;3. Department of Computer Science, Department of Physics and Astronomy, Hotchkiss Brain Institute, Alberta Children’s Research Hospital, University of Calgary, Calgary, AB, Canada;1. Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing 100084, China;2. Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China;3. State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China;4. University of Chinese Academy of Sciences, Beijing 100049, China;5. Shandong Provincial Key Laboratory of Animal Cell and Developmental Biology, School of Life Sciences, Shandong University, Qingdao 266237, China;6. IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China;1. Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel;2. Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel;1. Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA;2. Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA;3. Department of Cell and Developmental Biology, University of California San Diego, La Jolla, CA 92093, USA
Abstract:
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  • Keywords:microbiota  metagenomics  16S sequencing  computational modeling  pharmacological exposures  hematopoietic cell transplantation
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