A temperate bacteriophage specific for strains ofAeromonas salmonicida possessing A-layer,a cell surface virulence factor |
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| Authors: | Edward E Ishiguro Teresa Ainsworth Robin E Harkness William W Kay Trevor J Trust |
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| Institution: | (1) Department of Biochemistry and Microbiology, University of Victoria, V8W 2Y2 Victoria, British Columbia, Canada |
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| Abstract: | A temperate bacteriophage designated TP446 was isolated from culture supernatants ofAeromonas salmonicida strain A446. Phage TP446 adsorbed to all of the typical and atypical strains ofA. salmonicida tested that possessed A-layer, the surface protein array that represents the primary virulence factor of this fish pathogen. In contrast, TP446 failed to adsorb to mutants lacking A-layer. These results indicate that the A-layer is a component of the receptor for phage TP446. |
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