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Digit ratios by computer-assisted analysis confirm lack of anatomical evidence of prenatal androgen exposure in clinical phenotypes of polycystic ovary syndrome |
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| Authors: | Marla E Lujan Amanda J Podolski Donna R Chizen Denis C Lehotay Roger A Pierson |
| Institution: | 1.Division of Nutritional Sciences,College of Agriculture of Life Sciences,Ithaca,USA;2.Obstetrics, Gynecology & Reproductive Sciences, College of Medicine,University of Saskatchewan,Saskatoon,Canada;3.Pathology, College of Medicine,University of Saskatchewan,Saskatoon,Canada |
| Abstract: | BackgroundWe recently showed that women with four clinical phenotypes of polycystic ovary syndrome (PCOS) do not demonstrate anatomical evidence of elevated prenatal androgen exposure as judged by a lower ratio of the index (2D) to ring (4D) finger. However, those findings conflicted with a previous study where women with PCOS had lower right hand 2D:4D compared to healthy female controls. Both these studies used Vernier calipers to measure finger lengths - a method recently shown to be less reliable at obtaining finger length measurements than computer-assisted analysis. |
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