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Iron supplying systems of Salmonella in diagnostics, epidemiology and infection
Authors:Robert Kingsley  Wolfgang Rabsch  Peter Stephens  Mark Roberts  Rolf Reissbrodt  Peter H. Williams
Affiliation:Department of Microbiology and Immunology, University of Leicester, Leicester, UK;Bundesinstitut für gesundheitlichen Verbraucherschutz und Veterinärmedizin, Wernigerode, Germany;Unilever Research, Colworth Laboratory, Sharnbrook, Bedford, UK;Medeva Vaccine Research Unit, Department of Biochemistry, Imperial College, London, UK;Robert Koch-Institut, Bereich Wernigerode, Wernigerode, Germany
Abstract:Abstract Well-known and newly characterised mechanisms, both endogenous and exogenous, for the uptake of iron by Salmonella are outlined, and their possible roles at various stages in infection are discussed. The contributions of a detailed understanding of iron supplying systems to techniques for diagnosis, epidemiology and disease management are described.
Keywords:Salmonella    Siderophore    Growth supplement    Infection    Vaccine
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