Rearrangements between the operators in the bacteriophage lambda |
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| Authors: | Frank H Stephenson and W Paul Diehl |
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| Institution: | (1) Department of Biochemistry and Biophysics, University of California, San Francisco, Medical School, 94143 San Francisco, CA, USA;(2) Department of Biology, San Diego State University, 92182 San Diego, CA, USA |
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| Abstract: | Summary The left operator mutant  v2s develops poorly during infection as a result of constitutive expression of the left operon. A revertant of v2s, designated iri, was found to contain an inversion of the cI region with the inversion endpoints to be within the lambda operators o
L and o
R. Formation of the inversion is facilitated by a translocation of right operator o
R
c
mutant sequence to the left operator in v2s. The inversion in iri positions wild-type o
R sequence at o
L returning control of the left operon to repression by the lambda cro repressor. |
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| Keywords: | |
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