Recombination Is Associated with an Outbreak of Novel Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Viruses in China |
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| Authors: | Mang Shi Edward C Holmes Manreetpal Singh Brar Frederick Chi-Ching Leung |
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| Institution: | Sydney Emerging Infections and Biosecurity Institute, School of Biological Sciences and Sydney Medical School, The University of Sydney, NSW, Australiaa;Fogarty International Center, National Institutes of Health, Bethesda, Maryland, USAb;School of Biological Sciences, The University of Hong Kong, Hong Kong, People''s Republic of Chinac;Bioinformatics Center, Nanjing Agricultural University, Nanjing, People''s Republic of Chinad |
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| Abstract: | In 2009 to 2010, there was a marked increase in the number of infections with highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) in China. Through phylogenetic analysis, we show that viruses from this outbreak originated from a single recombination event, illustrating the potential importance of this process for disease emergence. |
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