Rare and fleeting: an example of interspecific recombination in animal mitochondrial DNA |
| |
Authors: | Ciborowski Kate L Consuegra Sofía García de Leániz Carlos Beaumont Mark A Wang Jinliang Jordan William C |
| |
Institution: | Institute of Zoology, Regent's Park, London NW1 4RY, UK. |
| |
Abstract: | Recombination is thought to occur only rarely in animal mitochondrial DNA (mtDNA). However, detection of mtDNA recombination requires that cells become heteroplasmic through mutation, intramolecular recombination or 'leakage' of paternal mtDNA. Interspecific hybridization increases the probability of detecting mtDNA recombinants due to higher levels of sequence divergence and potentially higher levels of paternal leakage. During a study of historical variation in Atlantic salmon (Salmo salar) mtDNA, an individual with a recombinant haplotype containing sequence from both Atlantic salmon and brown trout (Salmo trutta) was detected. The individual was not an F1 hybrid but it did have an unusual nuclear genotype which suggested that it was a later-generation backcross. No other similar recombinant haplotype was found from the same population or three neighbouring Atlantic salmon populations in 717 individuals collected during 1948-2002. Interspecific recombination may increase mtDNA variability within species and can have implications for phylogenetic studies. |
| |
Keywords: | mitochondrial DNA interspecific recombination Atlantic salmon Salmo salar brown trout Salmo trutta |
本文献已被 PubMed 等数据库收录! |