Crystallographic evidence for dioxygen interactions with iron proteins |
| |
Authors: | M Arménia Carrondo Isabel Bento Pedro M Matias Peter F Lindley |
| |
Institution: | (1) Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Av. da República, 2781-901 Oeiras, Portugal |
| |
Abstract: | The interaction of dioxygen with iron plays a key role in many important biological processes, such as dioxygen transport
in the bloodstream and the reduction of dioxygen by iron in respiration. However, the catalytic mechanisms employed, for example
in ligand oxidation, are not fully understood at the current time despite intensive biochemical, spectroscopic and structural
studies. This review outlines the structural evidence obtained by X-ray crystallographic methods for the nature of the interactions
between dioxygen and the metal in iron-containing proteins. Proteins involved in iron transport or electron transfer are not
included. |
| |
Keywords: | Dioxygen X-ray crystallography |
本文献已被 SpringerLink 等数据库收录! |
|