(E)- and (Z)-1,2,4-triazolylchromanone oxime ethers as conformationally constrained antifungals |
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Authors: | Emami Saeed Falahati Mehraban Banifatemi Ali Amanlou Massoud Shafiee Abbas |
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Affiliation: | Department of Medicinal Chemistry, Faculty of Pharmacy, Mazandaran University of Medical Sciences, PO Box 48175-861, Sari, Iran. |
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Abstract: | A series of 1,2,4-triazolylchromanone oxime ethers were synthesized and tested for in vitro antifungal activity. Many of these derivatives exhibit high activity against Candida albicans, Saccharomyces cerevisiae, Aspergillus niger and Microsporum gypseum. |
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