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(E)- and (Z)-1,2,4-triazolylchromanone oxime ethers as conformationally constrained antifungals
Authors:Emami Saeed  Falahati Mehraban  Banifatemi Ali  Amanlou Massoud  Shafiee Abbas
Affiliation:Department of Medicinal Chemistry, Faculty of Pharmacy, Mazandaran University of Medical Sciences, PO Box 48175-861, Sari, Iran.
Abstract:A series of 1,2,4-triazolylchromanone oxime ethers were synthesized and tested for in vitro antifungal activity. Many of these derivatives exhibit high activity against Candida albicans, Saccharomyces cerevisiae, Aspergillus niger and Microsporum gypseum.
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