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Endogenous opiates and behavior: 2012
Institution:1. Chitkara College of Pharmacy, Chitkara University, Punjab, India;2. Government Pharmacy College, Seraj, Mandi, Himachal Pradesh, India;3. Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Benha University, Toukh, Egypt;4. Center of Excellence in Screening of Environmental Contaminants (CESEC), Benha University, Toukh, Egypt;5. Clinical Sciences Department, College of Medicine, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia;6. Forensic Medicine and Clinical Toxicology Department, College of Medicine, Cairo University, Cairo, Egypt;7. Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraydah, Saudi Arabia;8. Department of Clinical Pharmacy, College of Pharmacy, Prince Sattam bin Abdulaziz University, Alkharj, Saudi Arabia;9. Natural & Medical Sciences Research Centre, University of Nizwa, Nizwa, Oman;10. School of Health Science, University of Petroleum and Energy Studies, Dehradun, Uttarakhand, India;11. Department of Pharmaceutical Sciences, Pharmacy Program, Batterjee Medical College, Jeddah, Saudi Arabia;12. Pharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt;13. Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, Romania
Abstract:This paper is the thirty-fifth consecutive installment of the annual review of research concerning the endogenous opioid system. It summarizes papers published during 2012 that studied the behavioral effects of molecular, pharmacological and genetic manipulation of opioid peptides, opioid receptors, opioid agonists and opioid antagonists. The particular topics that continue to be covered include the molecular-biochemical effects and neurochemical localization studies of endogenous opioids and their receptors related to behavior (Section 2), and the roles of these opioid peptides and receptors in pain and analgesia (Section 3); stress and social status (Section 4); tolerance and dependence (Section 5); learning and memory (Section 6); eating and drinking (Section 7); alcohol and drugs of abuse (Section 8); sexual activity and hormones, pregnancy, development and endocrinology (Section 9); mental illness and mood (Section 10); seizures and neurologic disorders (Section 11); electrical-related activity and neurophysiology (Section 12); general activity and locomotion (Section 13); gastrointestinal, renal and hepatic functions (Section 14); cardiovascular responses (Section 15); respiration and thermoregulation (Section 16); and immunological responses (Section 17).
Keywords:Opiate receptors  Beta-endorphin  Enkephalins  Dynorphin  Orphanin FQ/nociceptin  Endomorphins
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