|
|||||
|
|
Vasopressin activates Akt/mTOR pathway in smooth muscle cells cultured in high glucose concentration |
|
| Authors: | Daniela K Montes Marianne Brenet Vanessa C Muñoz Patricia V Burgos Carolina I Villanueva Carlos D Figueroa Carlos B González |
| Institution: | 1. Department of Physiology, Universidad Austral de Chile, Valdivia 509-9200, Chile;2. Department of Anatomy, Histology and Pathology, Universidad Austral de Chile, Valdivia 509-9200, Chile;3. Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX 77555, United States |
| Abstract: | Mammalian target of rapamycin (mTOR) complex is a key regulator of autophagy, cell growth and proliferation. Here, we studied the effects of arginine vasopressin (AVP) on mTOR activation in vascular smooth muscle cells cultured in high glucose concentration. |
| Keywords: | AVP arginine vasopressin mTOR mammalian target of rapamycin mTORC1 mTOR complex 1 PI3K phosphatidyl inositol-3 kinase AMPK AMP-activated protein kinase PKC protein kinase C Akt or protein kinase B TSC1/TSC2 tubero sclerosis protein 1 and 2 Rheb ras homolog enriched in brain PLD phospholipase D ERK extracellular regulated-kinase |
| 本文献已被 ScienceDirect 等数据库收录！ | |