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Proteomics of Asrij Perturbation in Drosophila Lymph Glands for Identification of New Regulators of Hematopoiesis
Institution:From the 3Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bangalore 560064, India;;4Institute of Bioinformatics, International Technology Park, Bangalore 560066, India;;5Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA;;6NIMHANS-IOB Proteomics and Bioinformatics Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bangalore 560029, India;;**Center for Systems Biology and Molecular Medicine, Yenepoya Research Center, Yenepoya (Deemed to be University), Mangalore-575018, India;;12Institute for Stem Cell Biology and Regenerative Medicine, GKVK, Bellary Road, Bangalore 560065, India
Abstract:
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  • Highlights
    • ?First report on the quantitative proteomic profiling of Drosophila lymph glands.
    • ?Comparative proteomic analysis under conditions of perturbed blood cell homeostasis.
    • ?Resource for identifying new regulators of insect and vertebrate hematopoiesis.
    Keywords:Drosophila melanogaster*  Blood*  Differentiation*  iTRAQ  Knockouts*  Mass Spectrometry  Asrij  hematopoiesis  lymph gland  proteome
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